Comparative analysis and correlation of cancer hotspot proteins and cell markers in tumor-normal adjacent breast and kidney samples using RPPA and LC-MS

Abstract Cancer proteomics is crucial for understanding tumor biology, yet consistent quantification of clinically relevant proteins across analytical platforms remains challenging. Here, we compared Reverse Phase Protein Array (RPPA) and Liquid Chromatography-Mass Spectrometry (LC-MS) using identic...

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Auteurs principaux:	Krisztina Paal, Noemi Karnok, Csaba Konrad, David Bui, Fanni Bugyi, Lilla Turiák, Christos Chinopoulos
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2026-05-01
Collection:	Scientific Reports
Sujets:	Liquid chromatography-mass spectrometry Oncogene Proteomics Reverse phase protein array Tumor-suppressor gene
Accès en ligne:	https://doi.org/10.1038/s41598-026-48754-2
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