ROS-responsive 3D biological scaffold delivers hypoxia-primed extracellular vesicles for targeted modulation of neuroinflammation in intracerebral hemorrhage

Abstract Background Emerging evidence suggests that paracrine mechanisms may underlie the therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles (EVs) (hUCMSC-exos) in mitigating neuroinflammation following intracerebral hemorrhage (ICH). Hypoxic preconditio...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Aobo Zhang, Dan Qiao, Ziyang Jia, Zhanzhan Zhang, Dongdong Yan, Chengrui Nan, Liqiang Liu, Yunpeng Shi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-10-01
Цуврал:	Stem Cell Research & Therapy
Нөхцлүүд:	3D biological scaffold Hypo-Exos Intracerebral hemorrhage Neuroinflammation miR-146b/COP1
Онлайн хандалт:	https://doi.org/10.1186/s13287-025-04691-x
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!