Massively parallel analysis of human 3′ UTRs reveals that AU-rich element length and registration predict mRNA destabilization
AbstractAU-rich elements (AREs) are 3′ UTR cis-regulatory elements that regulate the stability of mRNAs. Consensus ARE motifs have been determined, but little is known about how differences in 3′ UTR sequences that conform to these motifs affect their function. Here, we use functional annotation of...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2021-11-01
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| Col·lecció: | G3: Genes, Genomes, Genetics |
| Accés en línia: | https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab404 |
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