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Design and Synthesis of Novel β-catenin/BCL9 Protein–Protein Interaction Small Molecule Inhibitors for the Treatment of Colorectal Cancer

Colorectal cancer (CRC) is one of the most common gastrointestinal malignancies. The development of novel targeted drug therapeutics against CRC has been a research hotspot. Among these strategies, disrupting the β-catenin/BCL9 protein–protein interaction (PPI) emerges as a promising approach for th...

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Bibliografiska uppgifter
Huvudupphov: Yuyan Long, Mengfei Wang, Qingwei Zhang
Materialtyp: Artigo
Språk:Inglês
Utgiven: Georg Thieme Verlag KG 2026-06-01
Serie:Pharmaceutical Fronts
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Länkar:http://www.thieme-connect.de/DOI/DOI?10.1055/a-2834-4404
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