Benzylisoquinoline alkaloids inhibit lung fibroblast activation mainly via inhibiting TGF-β1/Smads and ERK1/2 pathway proteins

Backgrounds: Liensinine (Lien), Neferine (Nef), Isoliensinine (Iso) and Tetrandrine (Tet), benzylisoquinoline alkaloids (BIAs), have been shown inhibitory effects on pulmonary fibrosis (PF) through anti-inflammatory, anti-oxidative activities, inhibition of cytokines and NF-κB. Effects of other simi...

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Библиографические подробности

Главные авторы:	Hui-Li Ren, Jia-Hua Zhang, Jun-Hua Xiao
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2023-06-01
Серии:	Heliyon
Предметы:	Benzylisoquinoline alkaloids Lung fibroblasts Pulmonary fibrosis TGF-β1 Smad3/4 p-ERK1/2
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2405844023040562
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