SMAD2 inhibits pyroptosis of fibroblast-like synoviocytes and secretion of inflammatory factors via the TGF-β pathway in rheumatoid arthritis
Abstract Objective Rheumatoid arthritis (RA) is a chronic, progressive autoimmune disease. Over-activation of fibroblast-like synoviocytes is responsible for the hyperplasia of synovium and destruction of cartilage and bone and pyroptosis of FLS plays a key role in those pathological processes durin...
Gardado en:
| Principais autores: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMC
2023-08-01
|
| Series: | Arthritis Research & Therapy |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1186/s13075-023-03136-1 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|