Resistance Mutations to Broadly Neutralizing Antibodies Destabilize Hemagglutinin and Attenuate H1N1 Influenza Virus
Because antigenic drift primarily generates amino-acid changes in the membrane-distal hemagglutinin (HA) head, broadly neutralizing antibodies (bNAbs) are being developed to target conserved epitopes in the membrane-proximal stem. Mutations to HA2 residue A44, a buried residue beneath the central st...
Na minha lista:
| Principais autores: | , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI AG
2025-12-01
|
| Serier: | Viruses |
| Fag: | |
| Online adgang: | https://www.mdpi.com/1999-4915/18/1/32 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|
