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NKG2D Signaling Leads to NK Cell Mediated Lysis of Childhood AML

Natural killer cells have been shown to be relevant in the recognition and lysis of acute myeloid leukemia. In childhood acute lymphoblastic leukemia, it was shown that HLA I expression and KIR receptor-ligand mismatch significantly impact ALL cytolysis. We characterized 14 different primary childho...

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Bibliografiske detaljer
Principais autores: Patrick Schlegel, Kerstin Ditthard, Peter Lang, Markus Mezger, Sebastian Michaelis, Rupert Handgretinger, Matthias Pfeiffer
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2015-01-01
Serier:Journal of Immunology Research
Online adgang:http://dx.doi.org/10.1155/2015/473175
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