BAP1 loss impairs IFN-γ signaling and enhances NK cell-mediated cytotoxicity in myeloid leukemia
Abstract Natural killer (NK) cells recognize and eliminate malignant cells through multiple receptor–ligand interactions. To uncover genetic determinants of the susceptibility of myeloid leukemia cells to NK cell cytotoxicity, we analyzed several genome-wide CRISPR screens. Among recurrent hits, the...
I tiakina i:
| Ngā kaituhi matua: | , , , , , , , |
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| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Springer
2026-06-01
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| Rangatū: | Cancer Immunology, Immunotherapy |
| Ngā marau: | |
| Urunga tuihono: | https://doi.org/10.1007/s00262-026-04453-5 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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