SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis

TGF-β signaling regulates a variety of cellular processes, including proliferation, apoptosis, differentiation, immune responses, and fibrogenesis. Here, we describe a lysine methylation-mediated mechanism that controls the pro-fibrogenic activity of TGF-β. We find that the methyltransferase Set9 po...

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Principais autores:	Maximilianos Elkouris, Haroula Kontaki, Athanasios Stavropoulos, Anastasia Antonoglou, Kostas C. Nikolaou, Martina Samiotaki, Eszter Szantai, Dimitra Saviolaki, Peter J. Brown, Paschalis Sideras, George Panayotou, Iannis Talianidis
格式:	Artigo
语言:	Inglês
出版:	Elsevier 2016-06-01
丛编:	Cell Reports
在线阅读:	http://www.sciencedirect.com/science/article/pii/S2211124716306490
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