SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells

Abstract Background Abdominal aortic aneurysm (AAA) is a deadly cardiovascular disease characterised by the gradual, irreversible dilation of the abdominal aorta. AAA is a complex genetic disease but little is known about the role of epigenetics. Our objective was to determine if global DNA methylat...

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Bibliografski detalji

Glavni autori:	Bradley J. Toghill, Athanasios Saratzis, Peter J. Freeman, Nicolas Sylvius, UKAGS collaborators, Matthew J. Bown
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2018-03-01
Serija:	Clinical Epigenetics
Teme:	Epigenetics Vascular disease Aneurysm Inflammation
Online pristup:	http://link.springer.com/article/10.1186/s13148-018-0460-9
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