New 1,2,3-Triazole/1,2,4-triazole Hybrids as Aromatase Inhibitors: Design, Synthesis, and Apoptotic Antiproliferative Activity

A novel series of 1,2,3-triazole/1,2,4-triazole hybrids 5a, 5b, and 6a–i was designed and synthesized as antiproliferative agents targeting aromatase enzymes. The antiproliferative activity of the new hybrids against four cancer cells was studied using Erlotinib as a control. Compounds 6a and 6b dem...

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Principais autores:	Mohamed T-E Maghraby, Tahani Mazyad Almutairi, Stefan Bräse, Ola I. A. Salem, Bahaa G. M. Youssif, Mahmoud M. Sheha
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2023-10-01
Serija:	Molecules
Teme:	1,2,3-triazole 1,2,4-triazole anticancer aromatase viability
Online dostop:	https://www.mdpi.com/1420-3049/28/20/7092
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