New 1,2,3-Triazole/1,2,4-triazole Hybrids as Aromatase Inhibitors: Design, Synthesis, and Apoptotic Antiproliferative Activity

A novel series of 1,2,3-triazole/1,2,4-triazole hybrids 5a, 5b, and 6a–i was designed and synthesized as antiproliferative agents targeting aromatase enzymes. The antiproliferative activity of the new hybrids against four cancer cells was studied using Erlotinib as a control. Compounds 6a and 6b dem...

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Principais autores:	Mohamed T-E Maghraby, Tahani Mazyad Almutairi, Stefan Bräse, Ola I. A. Salem, Bahaa G. M. Youssif, Mahmoud M. Sheha
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2023-10-01
Series:	Molecules
Assuntos:	1,2,3-triazole 1,2,4-triazole anticancer aromatase viability
Acceso en liña:	https://www.mdpi.com/1420-3049/28/20/7092
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