Torpor induces reversible tau hyperphosphorylation and accumulation in mice expressing human tau
Abstract Tau protein hyperphosphorylation and aggregation are key pathological events in neurodegenerative tauopathies such as Alzheimer’s disease. Interestingly, seasonal hibernators show extensive tau hyperphosphorylation during torpor, i.e., the hypothermic and hypometabolic state of hibernation,...
שמור ב:
| Principais autores: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BMC
2024-06-01
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| סדרה: | Acta Neuropathologica Communications |
| נושאים: | |
| גישה מקוונת: | https://doi.org/10.1186/s40478-024-01800-4 |
| תגים: |
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