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Sequence and supercoiling-dependent effects on the structural dynamics of DNA minicircles

The degree of over-/underwinding of the DNA double helix, quantified by the superhelical density, is a key feature modulating critical biological processes such as gene expression and regulation. In fact, DNA molecules are able to channel the excess levels of mechanical stress into local defective a...

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Bibliografiske detaljer
Principais autores: Manuel Micheloni, Luca Tubiana, Raffaello Potestio, Lorenzo Petrolli
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-12-01
Serier:Biophysical Reports
Online adgang:http://www.sciencedirect.com/science/article/pii/S2667074725000412
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