Activation of AMPK by bitter melon triterpenoids involves CaMKKβ.

We recently showed that bitter melon-derived triterpenoids (BMTs) activate AMPK and increase GLUT4 translocation to the plasma membrane in vitro, and improve glucose disposal in insulin resistant models in vivo. Here we interrogated the mechanism by which these novel compounds activate AMPK, a leadi...

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主要な著者:	Tristan J Iseli, Nigel Turner, Xiao-Yi Zeng, Gregory J Cooney, Edward W Kraegen, Sheng Yao, Yang Ye, David E James, Ji-Ming Ye
フォーマット:	Artigo
言語:	Inglês
出版事項:	Public Library of Science (PLoS) 2013-01-01
シリーズ:	PLoS ONE
オンライン･アクセス:	http://europepmc.org/articles/PMC3636144?pdf=render
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