Overexpressed PKM2 promotes macrophage phagocytosis and atherosclerosis
Abstract Background The expression of pyruvate kinase muscle 2 (PKM2) is augmented in macrophages of patients with atherosclerotic coronary artery disease. The role of PKM2 in atherosclerosis is to be determined. Methods Global and myeloid cell‐specific PKM2 knock‐in mice with ApoE−/− background (Ap...
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| Principais autores: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Wiley
2023-04-01
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| Series: | Animal Models and Experimental Medicine |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1002/ame2.12266 |
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