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Overexpressed PKM2 promotes macrophage phagocytosis and atherosclerosis

Abstract Background The expression of pyruvate kinase muscle 2 (PKM2) is augmented in macrophages of patients with atherosclerotic coronary artery disease. The role of PKM2 in atherosclerosis is to be determined. Methods Global and myeloid cell‐specific PKM2 knock‐in mice with ApoE−/− background (Ap...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xiaochen Gai, Fangming Liu, Yuting Wu, Baohui Zhang, Bufu Tang, Kezhuo Shang, Lianmei Wang, Haihong Zhang, Yixin Chen, Shuhui Yang, Weiwei Deng, Peng Li, Jing Wang, Hongbing Zhang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley 2023-04-01
Cyfres:Animal Models and Experimental Medicine
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1002/ame2.12266
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!