Cross-species rescue reveals sequence requirements for a rapidly evolving intrinsically disordered region.

Many proteins contain intrinsically disordered regions (IDRs) that are essential for their function but do not adopt a stable structure; instead, they exist as an ensemble of conformations. Because these regions lack fixed structural constraints, traditional structure-based and alignment-based appro...

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Bibliografski detalji

Glavni autori:	Sang On Park, Rishad Khondker, Ariel Blank, Annie Dyatel, Corey Frazer, Richard J Bennett, Robert J D Reid, Rodney Rothstein, Luke E Berchowitz
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2025-09-01
Serija:	PLoS Biology
Online pristup:	https://doi.org/10.1371/journal.pbio.3003396
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