Revisiting the central metabolism of the bloodstream forms of Trypanosoma brucei: production of acetate in the mitochondrion is essential for parasite viability.

BACKGROUND: The bloodstream forms of Trypanosoma brucei, the causative agent of sleeping sickness, rely solely on glycolysis for ATP production. It is generally accepted that pyruvate is the major end-product excreted from glucose metabolism by the proliferative long-slender bloodstream forms of the...

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Principais autores:	Muriel Mazet, Pauline Morand, Marc Biran, Guillaume Bouyssou, Pierrette Courtois, Sylvie Daulouède, Yoann Millerioux, Jean-Michel Franconi, Philippe Vincendeau, Patrick Moreau, Frédéric Bringaud
格式:	Artigo
語言:	Inglês
出版:	Public Library of Science (PLoS) 2013-01-01
叢編:	PLoS Neglected Tropical Diseases
在線閱讀:	http://europepmc.org/articles/PMC3868518?pdf=render
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