Revisiting the central metabolism of the bloodstream forms of Trypanosoma brucei: production of acetate in the mitochondrion is essential for parasite viability.

BACKGROUND: The bloodstream forms of Trypanosoma brucei, the causative agent of sleeping sickness, rely solely on glycolysis for ATP production. It is generally accepted that pyruvate is the major end-product excreted from glucose metabolism by the proliferative long-slender bloodstream forms of the...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Muriel Mazet, Pauline Morand, Marc Biran, Guillaume Bouyssou, Pierrette Courtois, Sylvie Daulouède, Yoann Millerioux, Jean-Michel Franconi, Philippe Vincendeau, Patrick Moreau, Frédéric Bringaud
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:	PLoS Neglected Tropical Diseases
Online-Zugang:	http://europepmc.org/articles/PMC3868518?pdf=render
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!