Calycosin Orchestrates Osteogenesis of Danggui Buxue Tang in Cultured Osteoblasts: Evaluating the Mechanism of Action by Omics and Chemical Knock-out Methodologies

Danggui Buxue Tang (DBT), an ancient Chinese herbal decoction commonly used to mitigate menopausal osteoporosis, contains two herbs: Astragali Radix (AR) and Angelicae Sinensis Radix (ASR). The exact efficacy of individual chemical(s) within DBT, or in any herbal mixture, is hard to be revealed. Cal...

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Principais autores:	Amy G. W. Gong, Ran Duan, Huai Y. Wang, Tina T. X. Dong, Karl W. K. Tsim
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2018-02-01
Serija:	Frontiers in Pharmacology
Teme:	Astragali Radix Angelicae Sinensis Radix Danggui Buxue Tang RNA-seq metabolomics osteoblast
Online dostop:	http://journal.frontiersin.org/article/10.3389/fphar.2018.00036/full
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