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Upregulation of Siglec-6 induces mitochondrial dysfunction by promoting GPR20 expression in early-onset preeclampsia

Abstract Background Preeclampsia, especially early-onset preeclampsia (EO-PE), is a pregnancy complication that has serious consequences for the health of both the mother and the fetus. Although abnormal placentation due to mitochondrial dysfunction is speculated to contribute to the development of...

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Principais autores: Yuanhui Jia, Wenjing Lu, Han Xie, Yifan Sheng, Luyao Wang, Wenqi Lv, Lijun Ling, Jiaqi Dong, Xinrui Jia, Shengyu Wu, Wenqiang Liu, Hao Ying
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-07-01
Serier:Journal of Translational Medicine
Fag:
Preeclampsia
Early-onset preeclampsia
Extravillous trophoblast
Mitochondria
Siglec-6
GPR20
Online adgang:https://doi.org/10.1186/s12967-024-05505-z
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