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Uncovering new insights into the role of the ubiquitin ligase Smurf1 on the regulation of innate immune signaling and resistance to infection

Innate immunity is the body’s first line of defense against infections. Innate immune cells express pattern recognition receptors in distinct cellular compartments that are responsible to detect either pathogens-associated molecules or cellular components derived from damaged cells, to trigger intra...

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Auteurs principaux: Luiz Pedro Souza-Costa, Josiane Teixeira Andrade-Chaves, Juvana Moreira Andrade, Vivian Vasconcelos Costa, Luis Henrique Franco
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2023-05-01
Collection:Frontiers in Immunology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1185741/full
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