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Regulation of CNKSR2 protein stability by the HECT E3 ubiquitin ligase Smurf2, and its role in breast cancer progression

Abstract Background Smurf2 E3 ubiquitin ligase physically associates with and regulate the stability of distinct cellular protein substrates. The multi-functional scaffold protein Connector enhancer of kinase suppressor of ras 2 (CNKSR2) plays a key role in regulating cell proliferation, and differe...

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Váldodahkkit: Diana David, Arun Surendran, Jissa V. Thulaseedharan, Asha S. Nair
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2018-03-01
Ráidu:BMC Cancer
Fáttát:
Liŋkkat:http://link.springer.com/article/10.1186/s12885-018-4188-x
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