Synthesis and In Vitro Antitumor Activity Evaluation of Gefitinib-1,2,3-Triazole Derivatives

In this study, 14 structurally novel gefitinib-1,2,3-triazole derivatives were synthesized using a click chemistry approach and characterized by ¹H NMR, ¹³C NMR and high-resolution mass spectrometry (HRMS). Preliminary cell counting kit-8 results showed that most of the compoun...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Zijun Liu, Jiancheng Liu, En Gao, Longfei Mao, Shu Hu, Sanqiang Li
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2024-02-01
Sarja:	Molecules
Aiheet:	gefitinib 1,2,3-triazole antitumor drug cell apoptosis cell migration
Linkit:	https://www.mdpi.com/1420-3049/29/4/837
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