Development and characterization of an inducible Tensin1 deficient transgenic murine model

Abstract Tensin1 (TNS1) is a key component of focal and fibrillar adhesions, mediating fibrillogenesis, as well as the transduction of mechanical cues and adhesive signaling. To enable further TNS1 characterization, we have developed a novel transgenic mouse that allows for temporally controlled and...

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Hauptverfasser:	Ksenija Bernau, Kelsey Holbert, Ivy S. McDermott, Babita Rahar, Kade W. Coulter, Madalyn A. Osterhaus, Thomas J. Harr, Carson Gehl, Angie Tebon Oler, Christopher Huffman, Beth Gray, Trevor S. Langel, Kenneth M. Chan, Amir Forati, Sandra Splinter BonDurant, Mark E. Berres, Kathy J. Krentz, C. Dustin Rubinstein, Andres F. Mejia, Nathan Sandbo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2026-02-01
Schriftenreihe:	Scientific Reports
Online-Zugang:	https://doi.org/10.1038/s41598-026-41319-3
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