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Development and characterization of an inducible Tensin1 deficient transgenic murine model

Abstract Tensin1 (TNS1) is a key component of focal and fibrillar adhesions, mediating fibrillogenesis, as well as the transduction of mechanical cues and adhesive signaling. To enable further TNS1 characterization, we have developed a novel transgenic mouse that allows for temporally controlled and...

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Библиографические подробности
Главные авторы: Ksenija Bernau, Kelsey Holbert, Ivy S. McDermott, Babita Rahar, Kade W. Coulter, Madalyn A. Osterhaus, Thomas J. Harr, Carson Gehl, Angie Tebon Oler, Christopher Huffman, Beth Gray, Trevor S. Langel, Kenneth M. Chan, Amir Forati, Sandra Splinter BonDurant, Mark E. Berres, Kathy J. Krentz, C. Dustin Rubinstein, Andres F. Mejia, Nathan Sandbo
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Portfolio 2026-02-01
Серии:Scientific Reports
Online-ссылка:https://doi.org/10.1038/s41598-026-41319-3
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