Activation of CXCR3+ Tfh cells and B cells in lymph nodes during acute HIV-1 infection correlates with HIV-specific antibody development

ABSTRACT Lymph node T follicular helper (Tfh) cells and germinal center (GC) B cells are critical to generate potent antibodies but are rarely possible to study in humans. To understand how Tfh/GC B-cell interactions during acute HIV-1 infection (AHI) impact the generation of HIV-specific antibodies...

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প্রধান লেখক:	Julie L. Mitchell, Supranee Buranapraditkun, Pierre Gantner, Hiroshi Takata, Kenneth Dietze, Kombo F. N'guessan, Justin Pollara, Junsuke Nohara, Roshell Muir, Eugene Kroon, Suteeraporn Pinyakorn, Nicha Tulmethakaan, Sopark Manasnayakorn, Suthat Chottanapund, Pattarawat Thantiworasit, Peeriya Prueksakaew, Nisakorn Ratnaratorn, Suwanna Puttamaswin, Bessara Nuntapinit, Lawrence Fox, Elias K. Haddad, Dominic Paquin-Proulx, Praphan Phanuphak, Carlo P. Sacdalan, Nittaya Phanuphak, Jintanat Ananworanich, Denise Hsu, Sandhya Vasan, Guido Ferrari, Nicolas Chomont, Lydie Trautmann
বিন্যাস:	Artigo
ভাষা:	Inglês
প্রকাশিত:	American Society for Microbiology 2025-03-01
মালা:	Journal of Virology
বিষয়গুলি:	human immunodeficiency virus Tfh cells B-cell responses humoral immunity lymph node
অনলাইন ব্যবহার করুন:	https://journals.asm.org/doi/10.1128/jvi.01532-24
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