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Multiplexin promotes heart but not aorta morphogenesis by polarized enhancement of slit/robo activity at the heart lumen.

The Drosophila heart tube represents a structure that similarly to vertebrates' primary heart tube exhibits a large lumen; the mechanisms promoting heart tube morphology in both Drosophila and vertebrates are poorly understood. We identified Multiplexin (Mp), the Drosophila orthologue of mammalian C...

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Bibliografiset tiedot
Päätekijät: Nofar Harpaz, Elly Ordan, Karen Ocorr, Rolf Bodmer, Talila Volk
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2013-06-01
Sarja:PLoS Genetics
Linkit:https://doi.org/10.1371/journal.pgen.1003597
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