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Tissue‐Specific Roles for the Slit–Robo Pathway During Heart, Caval Vein, and Diaphragm Development

Background Binding of Slit ligands to their Robo receptors regulates signaling pathways that are important for heart development. Genetic variants in ROBO1and ROBO4 have been linked to congenital heart defects in humans. These defects are recapitulated in mouse models with ubiquitous deletions of th...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Juanjuan Zhao, Susann Bruche, Helen G. Potts, Benjamin Davies, Mathilda T. M. Mommersteeg
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Wiley 2022-04-01
Rangatū:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Ngā marau:
Urunga tuihono:https://www.ahajournals.org/doi/10.1161/JAHA.121.023348
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