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Tissue‐Specific Roles for the Slit–Robo Pathway During Heart, Caval Vein, and Diaphragm Development

Background Binding of Slit ligands to their Robo receptors regulates signaling pathways that are important for heart development. Genetic variants in ROBO1and ROBO4 have been linked to congenital heart defects in humans. These defects are recapitulated in mouse models with ubiquitous deletions of th...

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Bibliografische gegevens
Hoofdauteurs: Juanjuan Zhao, Susann Bruche, Helen G. Potts, Benjamin Davies, Mathilda T. M. Mommersteeg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wiley 2022-04-01
Reeks:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
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Online toegang:https://www.ahajournals.org/doi/10.1161/JAHA.121.023348
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