Matrix Nanopatterning Regulates Mesenchymal Differentiation through Focal Adhesion Size and Distribution According to Cell Fate

Extracellular matrix remodeling plays a pivotal role during mesenchyme patterning into different lineages. Tension exerted from cell membrane receptors bound to extracellular matrix ligands is transmitted by the cytoskeleton to the cell nucleus inducing gene expression. Here, we used dendrimer-based...

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Библиографические подробности

Главные авторы:	Ignasi Casanellas, Anna Lagunas, Yolanda Vida, Ezequiel Pérez-Inestrosa, José A. Andrades, José Becerra, Josep Samitier
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2019-06-01
Серии:	Biomimetics
Предметы:	arginine–glycine–aspartic acid (RGD) nanopattern mesenchymal stem cells tenogenesis osteogenesis cell nuclei focal adhesions
Online-ссылка:	https://www.mdpi.com/2313-7673/4/2/43
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