Towards inferring nanopore sequencing ionic currents from nucleotide chemical structures
Nanopore sequencing allows users to identify nucleotide sequence from ionic currents. Here, the authors use deep learning to facilitate the de novo identification of modified nucleotides, particularly methylated cytosine and guanine, from the measured ionic currents without the need for controls.
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2021-11-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-021-26929-x |
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