Transferability of polygenic risk scores for metabolic and cardiovascular traits in an underrepresented population
Abstract Polygenic risk scores (PRSs) are promising tools for genetic risk stratification, but their performance across ancestries remains uncertain. We evaluated 64 published PRSs for eight cardiometabolic traits in 4879 Thai individuals using imputed SNP-array data. Cross-sectional and six-year lo...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Portfolio
2025-11-01
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| Schriftenreihe: | npj Genomic Medicine |
| Online-Zugang: | https://doi.org/10.1038/s41525-025-00532-1 |
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