Pioglitazone Protects Against Renal Ischemia-Reperfusion Injury via the AMP-Activated Protein Kinase-Regulated Autophagy Pathway

Renal ischemia-reperfusion injury (IRI) is a major cause of acute renal failure. Our previous studies have shown that pioglitazone, a peroxisome proliferators-activated receptor (PPAR)-γ agonist used in type 2 diabetes, protects against renal IRI; however, the molecular mechanism underlying the reno...

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Detalhes bibliográficos

Principais autores:	Wenlin Chen, Xiaoqing Xi, Shuangyang Zhang, Cong Zou, Renrui Kuang, Zhenfeng Ye, Yawei Huang, Honglin Hu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-08-01
coleção:	Frontiers in Pharmacology
Assuntos:	pioglitazone renal ischemia reperfusion injury peroxisome proliferators-activated receptor-γ autophagy cell apoptosis
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphar.2018.00851/full
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