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Maslinic Acid Attenuates Ischemia/Reperfusion-Induced Acute Kidney Injury by Suppressing Inflammation and Apoptosis Through Inhibiting NF-κB and MAPK Signaling Pathway

Inflammation and apoptosis are the major contributors to the mechanisms of acute kidney injury (AKI) due to renal ischemia-reperfusion injury (IRI). Maslinic acid (MA), a pentacyclic triterpene acid mostly found in dietary plants, the current study was to demonstrate the renoprotective effect of MA...

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Main Authors: Wenjuan Sun, Hong Sang Choi, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
ischemia-reperfusion injury
maslinic acid
NF-κB
MAPK
kidney diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.807452/full
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