Cardiolipin remodelling in mitochondrial therapeutics: translational evidence chains from elamipretide to emerging strategies

Mitochondrial therapeutics have repeatedly fallen short of disease modification, in part because inner-membrane architecture constrains both molecular access and the reversibility of bioenergetic failure. Cardiolipin (CL), the signature phospholipid of the inner mitochondrial membrane, provides a me...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Ke Di, Yusheng Hu, Hechen Sun, Tianwei Meng, Tingquan Han, Rui Qie
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2026-05-01
Schriftenreihe:	Frontiers in Physiology
Schlagworte:	cardiolipin cardiolipin remodelling elamipretide inner mitochondrial membrane target engagement
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphys.2026.1813119/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!