Cardiolipin remodelling in mitochondrial therapeutics: translational evidence chains from elamipretide to emerging strategies

Mitochondrial therapeutics have repeatedly fallen short of disease modification, in part because inner-membrane architecture constrains both molecular access and the reversibility of bioenergetic failure. Cardiolipin (CL), the signature phospholipid of the inner mitochondrial membrane, provides a me...

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Váldodahkkit:	Ke Di, Yusheng Hu, Hechen Sun, Tianwei Meng, Tingquan Han, Rui Qie
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2026-05-01
Ráidu:	Frontiers in Physiology
Fáttát:	cardiolipin cardiolipin remodelling elamipretide inner mitochondrial membrane target engagement
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fphys.2026.1813119/full
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