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Loss of RNase J leads to multi-drug tolerance and accumulation of highly structured mRNA fragments in Mycobacterium tuberculosis.

Despite the existence of well-characterized, canonical mutations that confer high-level drug resistance to Mycobacterium tuberculosis (Mtb), there is evidence that drug resistance mechanisms are more complex than simple acquisition of such mutations. Recent studies have shown that Mtb can acquire no...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Maria Carla Martini, Nathan D Hicks, Junpei Xiao, Maria Natalia Alonso, Thibault Barbier, Jaimie Sixsmith, Sarah M Fortune, Scarlet S Shell
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2022-07-01
Rangatū:PLoS Pathogens
Urunga tuihono:https://doi.org/10.1371/journal.ppat.1010705
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