Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors

Primary cilia are microtubule-based organelles, which protrude from the plasma membrane and receive a wide range of extracellular signals. Various cilia use G protein-coupled receptors (GPCRs) for the detection of these signals. For instance, vertebrate rod photoreceptors use their cilia (also calle...

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Autores principales:	Celine Brooks, Joseph Murphy, Marycharmain Belcastro, Daniel Heller, Saravanan Kolandaivelu, Oleg Kisselev, Maxim Sokolov
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2018-01-01
Colección:	Frontiers in Molecular Neuroscience
Materias:	retina rod photoreceptor heterotrimeric G protein farnesylation protein trafficking cilium
Acceso en línea:	https://www.frontiersin.org/article/10.3389/fnmol.2018.00016/full
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