The cardioprotective effects of secoisolariciresinol diglucoside (flaxseed lignan) against cafeteria diet-induced cardiac fibrosis and vascular injury in rats: an insight into apelin/AMPK/FOXO3a signaling pathways

Introduction: Fast food is a major risk factor for atherosclerosis, a leading cause of morbidity and mortality in the Western world. Apelin, the endogenous adipokine, can protect against cardiovascular disease via activating its receptor, APJ. Concurrently, secoisolariciresinol diglucoside (SDG), a...

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Autores principales:	Azza H. Abdelwahab, Amira M. Negm, Eman S. Mahmoud, Rania M. Salama, Mona F. Schaalan, Azza A. K. El-Sheikh, Basma K. Ramadan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2023-07-01
Colección:	Frontiers in Pharmacology
Materias:	flaxseed secoisolariciresinol diglucoside apelin dyslipidemia vascular injury cardiac fibrosis
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1199294/full
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