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Amyloid pathology induces dysfunction of systemic neurotransmission in aged APPswe/PS2 mice

This study aimed to investigate how amyloid pathology affects the functional aspects of neurotransmitter systems in Alzheimer’s disease. APPswe/PS2 mice (21 months of age) and wild-type (WT) mice underwent positron emission tomography (PET) and magnetic resonance spectroscopy (MRS). First, we obtain...

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Principais autores: Se Jong Oh, Namhun Lee, Kyung Rok Nam, Kyung Jun Kang, Sang Jin Han, Kyo Chul Lee, Yong Jin Lee, Jae Yong Choi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-08-01
coleção:Frontiers in Neuroscience
Assuntos:
positron emission tomography
Alzheimer’s disease
APPswe/PS2
beta amyloid
neurotransmitter
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnins.2022.930613/full
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