Intermittent hypoxia treatment alleviates memory impairment in the 6-month-old APPswe/PS1dE9 mice and reduces amyloid beta accumulation and inflammation in the brain

Abstract Background Alzheimer’s disease (AD) is a progressive, degenerative, and terminal disease without cure. There is an urgent need for a new strategy to treat AD. The aim of this study was to investigate the effects of intermittent hypoxic treatment (IHT) on cognitive functions in a mouse model...

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Principais autores:	Xiangpei Yue, Yanzhao Zhou, Meng Qiao, Xingnan Zhao, Xin Huang, Tong Zhao, Xiang Cheng, Ming Fan, Yongqi Zhao, Ruoli Chen, Lingling Zhu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-11-01
coleção:	Alzheimer’s Research & Therapy
Assuntos:	Alzheimer’s disease APPswe/PS1dE9 mice Intermittent hypoxia treatment Amyloid beta BACE1 Neuroinflammation
Acesso em linha:	https://doi.org/10.1186/s13195-021-00935-z
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