Serum anti-malondialdehyde-acetaldehyde IgA antibody concentration improves prediction of coronary atherosclerosis beyond traditional risk factors in patients with rheumatoid arthritis

Abstract Patients with rheumatoid arthritis (RA) have increased atherosclerosis; oxidative stress may be a contributor. Oxidative stress produces immunogenic malondialdehyde-acetaldehyde (MAA) protein adducts and anti-MAA antibodies are detectable in human serum. We hypothesized that anti-MAA antibo...

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Bibliografische Detailangaben

Hauptverfasser:	Hannah E. Lomzenski, Geoffrey M. Thiele, Michael J. Duryee, Sheau-Chiann Chen, Fei Ye, Daniel R. Anderson, Ted R. Mikuls, Michelle J. Ormseth
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2022-06-01
Schriftenreihe:	Scientific Reports
Online-Zugang:	https://doi.org/10.1038/s41598-022-14954-9
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