Citrullinated and Malondialdehyde–Acetaldehyde-Modified Fibrinogen Activates Macrophages and Promotes Coronary Endothelial Cell Inflammation

Individuals with rheumatoid arthritis (RA) face increased cardiovascular mortality due to heart failure (HF) complications. Post-translational modifications, such as citrullination (CIT) and malondialdehyde–acetaldehyde (MAA) adduction, are implicated in RA pathogenesis. However, their role in RA-as...

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Bibliografische Detailangaben

Hauptverfasser:	Wenxian Zhou, Hannah J. Johnson, Michael J. Duryee, Nozima Aripova, Engle E. Sharp, Carlos D. Hunter, Kimberley Sinanan, Henry C. Drvol, Mason G. Feely, Tate M. Johnson, Mabruka Alfaidi, Daniel R. Anderson, Vineeth K. Reddy, Keshore Bidasee, Robert G. Bennett, Jill A. Poole, Geoffrey M. Thiele, Ted R. Mikuls
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-11-01
Schriftenreihe:	Current Issues in Molecular Biology
Schlagworte:	malondialdehyde–acetaldehyde citrulline post-translational modifications rheumatoid arthritis heart failure endothelial cell
Online-Zugang:	https://www.mdpi.com/1467-3045/47/11/943
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