Citrullinated and Malondialdehyde–Acetaldehyde-Modified Fibrinogen Activates Macrophages and Promotes Coronary Endothelial Cell Inflammation

Individuals with rheumatoid arthritis (RA) face increased cardiovascular mortality due to heart failure (HF) complications. Post-translational modifications, such as citrullination (CIT) and malondialdehyde–acetaldehyde (MAA) adduction, are implicated in RA pathogenesis. However, their role in RA-as...

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Autori principali:	Wenxian Zhou, Hannah J. Johnson, Michael J. Duryee, Nozima Aripova, Engle E. Sharp, Carlos D. Hunter, Kimberley Sinanan, Henry C. Drvol, Mason G. Feely, Tate M. Johnson, Mabruka Alfaidi, Daniel R. Anderson, Vineeth K. Reddy, Keshore Bidasee, Robert G. Bennett, Jill A. Poole, Geoffrey M. Thiele, Ted R. Mikuls
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-11-01
Serie:	Current Issues in Molecular Biology
Soggetti:	malondialdehyde–acetaldehyde citrulline post-translational modifications rheumatoid arthritis heart failure endothelial cell
Accesso online:	https://www.mdpi.com/1467-3045/47/11/943
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