Short promoters in viral vectors drive selective expression in mammalian inhibitory neurons, but do not restrict activity to specific inhibitory cell-types

Short cell-type specific promoter sequences are important for targeted gene therapy and studies of brain circuitry. We report on the ability of short promoter sequences to drive fluorescent protein expression in specific types of mammalian cortical inhibitory neurons using adeno-associated virus (AA...

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Autors principals:	Jason L Nathanson, Roberto Jappelli, Eric D Scheeff, Gerard Manning, Kunihiko Obata, Sydney Brenner, Edward M Callaway
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2009-11-01
Col·lecció:	Frontiers in Neural Circuits
Matèries:	transcription factor Cortex Viral vector Promoter fugu inhibitory interneuron
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/neuro.04.019.2009/full
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