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Early Signs of Molecular Defects in iPSC-Derived Neural Stems Cells from Patients with Familial Parkinson’s Disease

Parkinson’s disease (PD) is the second most common neurodegenerative disorder, classically associated with extensive loss of dopaminergic neurons of the substantia nigra pars compacta. The hallmark of the disease is the accumulation of pathogenic conformations of the presynaptic protein, α-synuclein...

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Bibliografiske detaljer
Principais autores: Elissavet Akrioti, Timokratis Karamitros, Panagiotis Gkaravelas, Georgia Kouroupi, Rebecca Matsas, Era Taoufik
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-06-01
Serier:Biomolecules
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Online adgang:https://www.mdpi.com/2218-273X/12/7/876
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