Long-Term Evaluation of Intranigral Transplantation of Human iPSC-Derived Dopamine Neurons in a Parkinson’s Disease Mouse Model

Parkinson’s disease (PD) is a neurodegenerative disorder associated with loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). One strategy for treating PD is transplantation of DA neuroblasts. Significant advances have been made in generating midbrain DA neurons from human...

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Hauptverfasser:	Sébastien Brot, Nabila Pyrenina Thamrin, Marie-Laure Bonnet, Maureen Francheteau, Maëlig Patrigeon, Laure Belnoue, Afsaneh Gaillard
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-05-01
Schriftenreihe:	Cells
Schlagworte:	induced pluripotent stem cells dopaminergic neurons Parkinson’s disease brain repair recovery
Online-Zugang:	https://www.mdpi.com/2073-4409/11/10/1596
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